Isn't the whole point of venture capital that you take on a large risk in return for a large potential payout. VC is called "risk capital" in a number of languages for a reason.
But at some point the risk gets so large that the choice is for you to not get any investment at all, or get one with additional clauses to reduce the risk to levels acceptable to your potential investors.
It's a tradeoff. And sometimes it can work to your benefit. E.g. if you and your potential investor disagrees about the level of risk and/or about the potential size of an exit, you can try to negotiate a multiple liquidation preference in return for less shares.