NoScript gives you a chance to evaluate a site for trustworthiness. Yes, you have to click 1-2 times when you load a new domain that you trust, but it's worth it for that one site that looks sketchy or that you get mislead into clicking onto. For people who automatically execute JavaScript, it's already too late, but NoScript users have an opportunity to avoid this cantankerous situation.

NoScript will expose phishing schemes immediately, for instance, because it will recognize that the scripts being executed are not coming from the previously-whitelisted domain for Google.