A lot of brain diseases are proving difficult to treat due to the “blood-brain barrier”[1]. Could this bacteria be genetically modified to achieve this purpose? If so, the bacteria, when absorbed through the gums could be used benevolently to provide treatment for all sorts of brain diseases.
Something else to consider - what if the reason these plaques are unable to be cleaned out in some is the result of a life (decades)-long “deep” sleep deprivation (i.e, still getting sleep but not a good amount of regular, deep sleep where this cleaning process would normally occur), and the reason for this chronic sleep deprivation was some genetic pre-disposition, such as bruxism, which would cause little to no “deep sleep,” or perhaps brought on form of chronic dehydration due to a genetic predisposition for diabetes / sugary drinks / blood sugar imbalance, causing brain fogginess rather than deep sleep during a period of involuntary fasting, or a myriad of other unnoticeable deep- sleep-depriving illnesses?
I am not suggesting I have any answers; only questions and curiosities for the puzzling subject.
You're just considering "involuntary" lack of sleep, when there seems to be a serious epidemic of voluntary sleeplessness as indicated by frequent boasting about how little sleep one can get by on.
Chronic insomnia is still extremely poorly understood, unfortunately, and as other commentators have mentioned in this thread sleep medications are a short term bandage that come with their own harmful side-effects.
As someone who's a chronic insomniac and has been my entire life since I was a baby, I've tried almost everything to sleep with no success. At this point I'm still in my 20s and young, but I worry about having memory and health issues as I age. For now I'm just trying to stay healthy despite it and make a habit of documentation in case my memory does become compromised.
This is simply a disagreement between content publishers and content distributors. When a big satellite TV provider acted unfavorably toward a few major television networks during contract (re)-negotiation, those select few decided not to renew their license with the satellite TV company, causing viewers to ask why they can't get their favorite channel that their neighbor still gets.
The internet works similarly in that an electronic contract is formed when an ISP attempts to access content on web server. The client/ISP "requests" the content, and the publisher agrees and serves it up. But there's nothing stopping a collective "big few" from denying access to the content based on the host name of the ISP requesting it.
Ergo, if Verizon doesn't want to play "fair" with regards to content distribution, Facebook/Google/Twitter/Netflix/Reddit and whomever else could deny access to Verizon subscribers with an ol fashioned HTTP 403 or 401.
Yes, traffic drops, people realize quickly that they can't access any of their favorite sites, things must be broken, and switch companies.
Probably because the ad you linked is ... a lot more confusing than the other one. It's very fast-paced and shows a lot of various products, which to the average person watching the SuperBowl might be a bit much. The ad they aired showed not only how simple Google is, but also how powerful it is. I think it was a great mix.
Time and again, it's been shown that businesses who seem to truly care for their employees, or just the People in general, are richer than any business that cares only to turn a profit.
A big thank you to breadpig for its charitable efforts.
It's really just a ploy. You see, as people buy LOLmagnetz, more money gets donated to our local SPCA, which can save more cats and dogs, only to have them get adopted and create more pet owners, who will naturally be inclined to... buy LOLmagnetz.
Ta-da!
Admittedly, this just arose from a desire to create interesting stuff people wanted (it's such a calculable way to know someone likes what you've created). I suppose it's not far from the YC maxim.
We're in a lucky place because we don't need to do this to pay our own bills, so we can give it all away. But this element came from my frustration with how stale fundraising has become for most non-profits. People have become desensitized/jaded/bored by the typical plea of "help X, give $Y." Offering a product someone wants even without possibly knowing of the charitable implications (and I have anecdotal evidence to show that many don't know this about in our products) means a unique fundraising channel for the non-profits that benefit.
If I had my druthers, more people - especially nonprofits themselves - would copy not just our products (hehe) but also the model.
Oh, and as for caring for people, I am an avid believer in the great affect it has on business. But here's the best part, the bar has been set so low that you don't even need to care, just don't be a dick. Or put inversely, be reasonable and kind.
"...'Systematic' is the last word I'd use to describe the way good programmers write software. Code is not something they assemble painstakingly after careful planning, like the pyramids. It's something they plunge into, working fast and constantly changing their minds, like a charcoal sketch.
In software, paradoxical as it sounds, good craftsmanship means working fast. If you work slowly and meticulously, you merely end up with a very fine implementation of your initial, mistaken idea. Working slowly and meticulously is premature optimization. Better to get a prototype done fast, and see what new ideas it gives you. ..."
[1]: https://en.wikipedia.org/wiki/Blood–brain_barrier