> are malaria vaccines not interesting for drug companies because there's no money in them
Considering the nature of market economies and how the wealth is distributed in the world, it is not particularly surprising that most most medical research is aiming to cure ailments that affect white western men.
This is why the huge commitment from the Bill and Melinda Gates Foundation is such a huge boon. We see progress in the fight against malaria in the developing world for the first time in many decades.
As for the observation that companies only spend billions in research for markets where they can find can paying customers, I would say that others are free to raise money and start companies to cure other diseases. Even in the developed world, there are literally thousands of other diseases for which a handful of people that don't have large markets either. The WSJ ran a large article on this a year or so ago.
I agree with melling's comment here, and I wanted to add that malaria has been a difficult disease. Attempts to create a vaccine for it have been going on for decades. It is a disease caused by a parasite, not a virus nor a bacteria. No other parasitic disease has ever had a successful vaccine created for it.
Malaria lingers in infected people for their entire lives with periodic disabling relapses. The malaria antigens, that trigger the antibody response, are extremely variable and allow the malaria parasites to evade the body's immune system. It is surprising to me that any vaccine can be developed which is effective against it.
I was researching stuff for another post I was going to make (didn't end up making it), but I think it's worth adding an caveat to your point re parasitic vaccines, namely that we do have anti-parasitic vaccines for livestock [0]. This is not an attempt to down play the general difficulty of anti-parasitic vaccines in general, or of malaria especially. My understanding is that malaria is sufficiently nasty that even repeated childhood exposure typically only grants partial immunity - as opposed to say some other nasty like smallpox or measles which grants much fuller acquired immunity.
Considering the nature of market economies and how the wealth is distributed in the world, it is not particularly surprising that most most medical research is aiming to cure ailments that affect white western men.
This is why the huge commitment from the Bill and Melinda Gates Foundation is such a huge boon. We see progress in the fight against malaria in the developing world for the first time in many decades.