Yes. I had one. It died suddenly and left me with a £400 bill for a new one. Fortunately I backed up the NAS to an external disk but from this and other experiences, I've come to a general rule:
the reliability of a backup system is inversely proportional to the number of moving parts
Hence why I use beyond compare to manually sync files to two physical mediums from the master copy on my laptop. One encrypted USB stick I carry on me at all times and one hard disk that lives in a fire safe.