I would imagine that self driving cars will be much easier to design for accessibility seeing as other design considerations become less relevant (such as needing the driver to be in a certain position and facing the front in the vehicle). If I were to design an autonomous car today I would design it with one huge top hinged door on each side and a ramp that makes it easy to drive a wheelchair straight in. Have all the seats facing each other and ensure that at least one folds up/swivels to the side to make room for the wheelchair. This would also benefit people traveling with over-sized luggage.

The only thing Uber will get from this is bad PR. Their seeming arrogance (not only in this matter) is a real turn off.