I was thinking that both Eugene Wigner's 1960 article 'The Unreasonable Effectiveness of Mathematics in the Natural Sciences'[0] and Karpathy's 'The Unreasonable Effectiveness of Recurrent Neural Networks' probably touch deep aspects of the nature of existence. The first on why the universe exists and is mathematical - because at the fundamental level it is mathematical[1], and in Karpathy's case the RNNs are probably effective because they are close to the mechanisms of human consciousness.