However, many posting here are interested in the weight-management effects of treadmill desks.
If you are doing heavy caloric restriction then you probably don't have a weight management issue. It's worth noting that the longevity-effects of caloric restriction seem to start occurring at very restrictive levels of consumption, and few have the self-control to stay at that level for decades (which seems to be what is needed).
Intermittent Fasting and the 5:2 diets are good compromises. My concern with too much exercise is the tissue wear and the oxidative stress associated with aerobic exercise. There are studies that walking for 2 minutes every 20 minutes negates the negative effect of sitting. I personally tried 25 minute sitting work + walking for 5 minutes (which actually increases productivity when you stop staring at the screen without a break).
However, many posting here are interested in the weight-management effects of treadmill desks.
If you are doing heavy caloric restriction then you probably don't have a weight management issue. It's worth noting that the longevity-effects of caloric restriction seem to start occurring at very restrictive levels of consumption, and few have the self-control to stay at that level for decades (which seems to be what is needed).