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One of the things that make me wonder is the idea that there are " diseases if civilisation" (accepted, look at increases in asthma etc) and that they are caused by diet

Of all the things that exist in the modern world, lead in atmosphere, weird fungicides in our furniture fire retardants, etc, why is it the one thing that is under individual control that is the main contributor to our malease - it seems far too linked to the common "if you are ill / poor then you aren't trying hard enough" meme that Oprah et al tend to fall for.

Anyway, as a set of nutritional guidelines it seems reasonable, if only because the avergage food obsessed westerner has aceess to a range of fruit veg and meat that our ancestors never dreamed of.

Now stop trying to persuade me to agree with you so that I can be saved - it smacks of religion



I don't see the diet as being universally applicable but the theory behind the diet is compelling. There's an overlap in risk factors for diabetes, cancer, and heart disease. There's also an overlap in medications(e.g statins/aspirin lowering cancer risk. metformin lowering cancer risk). It's possible that all these diseases share biomolecular cascades.

http://robbwolf.com/2012/03/09/paleo-diet-inflammation-metfo...


My skepticism antennae are twitching

Firstly it has the tang of religion - we have found the answer, it requires certain rites and adherences and we must now persuade you to believe

Secondly it is highly highly unlikely an actual Stone Age person had access to the range of meat and vegetables currently in wegmans and so the question is which Stone Age diet? The one where they lived near a lake and had fish, the one where they had lots of vitamin C rich berries but few fish?

Thirdly evolution is slow but not glacial - 2.6m years is a long time, and frankly why go back that far and not further? At what point has evolution not caught up and how does that overlap with 'out of africa'?

Finally and th biggest question to me, is why assume that so many maleases are solely or primarily diet related. Obesity is pretty obvious but asthma? Cancer even?


>My skepticism antennae are twitching Firstly it has the tang of religion - we have found the answer, it requires certain rites and adherences and we must now persuade you to believe

I'm not sure how any of this addresses the claim that carbohydrates are a major cause of disease which is the only issue my post addressed.

http://www.youtube.com/watch?v=dBnniua6-oM

>Finally and th biggest question to me, is why assume that so many maleases are solely or primarily diet related. Obesity is pretty obvious but asthma? Cancer even?

A transitive relationship is being inferred.

There's evidence that cholesterol plaque build-up is driven by inflammation. There's evidence that many cancers are driven by inflammation. There's evidence that insulin spikes are involved in bio-molecular cascades for driving inflammation which are also involved in diabetes. Therefore carbohydrates are involved in inflammation which predisposes a person to cancer, heart disease, and diabetes. Proving anything beyond doubt in biology is difficult but it's a compelling hypothesis that needs further investigation.


They studied what happened to people who switched to agriculture 11000 years ago, via the fossil record. Also you can watch what happens to people who lived in a traditional way and then entered society.

That way I think a lot of things you mention can be excluded - not that lead and fire retardants are not dangerous, but that is another area of problems.


But we have no evidence that the diseases we wan to get rid of are diet driven, even obesity is amenable to better social cures than lets all eat this way.

Where can I find details on what did happen to people 11,000 years ago?


Yes we do. There was an article last week about how ingesting sugar has been categorically linked to diabetes - in the same way that smoking is linked to lung cancer.




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