I really hope Django gets support for persistent connections and/or connection pooling. pgbouncer isn't always an option on shared hosting (and is a royal PITA to setup on Windows) and there are other databases than postgres.
Here @ SendHub we've been using django-db-pool[0] since Q3 of 2012 in production and it's been pretty smooth sailing.
NB: I highly recommend verifying via postgres logs that the module is doing what you expect, because it may not be immediately clear whether the driver has bee activated or not.
I really hope Django gets support for persistent connections and/or connection pooling. pgbouncer isn't always an option on shared hosting (and is a royal PITA to setup on Windows) and there are other databases than postgres.