My Retina Macbook Pro 13" is my main machine and I connect 2 27" Viewsonic monitors to it daily. It works just fine for everyday work (iterm, vim, intellij, rdp and office apps)
If only it had 16GB (not available on the 13" rMBP model), it would be the perfect laptop
While it can drive two external displays, it only has one Thunderbolt port. The only easy way to attach multiple monitors is chaining Apple's Thunderbolt Displays. Other setups may require Thunderbolt docks or the like.