I've always used :x or :x! and no longer remember why. Probably it's a bad idea like without actually looking right now I think it might mean to ignore permissions (if you're root enough) and just write even if perms would have blocked it. Hm, maybe x means wq and just the ! means force.
The fact that everyone says the meme is dead, but in this small thread there are 5 different people posting how to exit, and none of them are the same says there is still pretty good substance behind that meme.
I feel like the default behavior should be to not write unless changes have been made. I may be misunderstanding here, but what would be getting written if nothing's been changed?