While it might not be normal, that type of thing is not unknown and alone is enough to mean everyone should avoid those drugs.

I disagree, I think it is effectively unknown, vanishingly rare considering how many millions of doses have been consumed over decades.

Let’s not pretend it’s 100% safe and foolproof, but that’s very far out of the ordinary.

That kind of thing occurs far more often when someone has not used drugs.

Logically, drug use should be mandatory to reduce the prevalence of such self-harm.

By your own logic you are fine with all alcohol being avoided, right? Psychedelics kill infinitely fewer people than alcohol, after all.