> If it's so easy, then why do people die from having lesions misdiagnosed as benign?
You're confusing False Negatives with True Negatives. For Non-Benign (Positive) vs. Benign (Negative) classification:
* True Positive Rate (TPR): non-benign classified as non-benign.
* False Positive Rate (FPR): benign misclassified as non-benign.
* True Negative Rate (TNR): benign classified as benign.
* False Negative Rate (FNR): non-benign misclassified as benign.
> It's quite easy to correctly classify 100% of benign cases as benign.
You can engineer a 100% TNR if you just classify everything as the "benign" negative class. The FNR is going to be 100% too, but that doesn't matter -- you correctly classified 100% of benign cases as benign.
> why do people die from having lesions misdiagnosed as benign?
Because the FNR is not 0%. FNR is important. You probably want a decent TPR in there as well. And FPR can be very important too, depending on how life-changing/painful/invasive the treatment for a positive case is!