I thought touching the math optimizations directly was in the "unsafe" bucket. Really the only optimization I was aiming for was -march=native. That and the features like native compilation that have made it to the release.
I do think I saw improvements. But I never got numbers, so I'm assuming most of my feel was wishful thinking. Reality is a modern computer is hella fast for something like emacs.
I did see compilation mode improve when I trimmed down the regexes it watches for to only the ones I knew were relevant for me. That said, I think I've stopped doing that; so maybe that is a lot better?
I've turned on fastmath in python numba compiler while thinking "of course i want faster math, duh". Took me a while to find out it was a cause of many "fun" subtle bugs. Never touching that stuff again.