I have a very close friend who's Chilean but grew up in Brasil after his family immigrated to escape Pinochet. Overall, Chile is exceptionally safe by South American standards, especially outside Santiago (which has all the perks and challenges of any large city).
It is very hot in Paraguay so I am waiting a while before I visit. Today I'm in Lima and eventually plan on visiting Salvador in Brazil. Asuncion has become one of the top destinations for digital nomads and I am curious what it is about this land locked country other than the very favorable tax laws that is attracting people.