There is no doubt that retinal ganglion cell death causes glaucoma. But you are right that what causes ganglion cells to die is more complex. Mitochondrial stress and metabolic decompensation are certainly critical. Axonal injury is a key trigger in many cases. High intraocular pressure is the most common cause for metabolic cellular stress leading to gsngliin cell death.
Yep. I worded it a bit awkwardly but that was what I was getting at. And mostly I was trying to make the distinction between damage within the "eyeball" vs more comprehensive damage further up the optic nerve as that distinction would determine how viable a transplant would be at recovering lost vision.
