High pixel count cameras aren't that useful in microscopy. Big low noise pixels are better. For every sensor there is already a breakout board with USB. Mostly intended for machine vision.

Edit: added link to Arducam USB cameras : https://www.arducam.com/product/arducam-64mp-motorized-focus... is a 64MP camera although note it's 1FPS. Instead I would prefer https://www.arducam.com/product/presalesarducam-8-3mp-imx585... which has C-mount that's perfect for scopes, it's 4K for still images, and the sensor is specifically designed for low light, when tends to be common in microscopy at higher magnifications./