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Maybe they work on some small subset of pain similarly, but they really are incomparable.

Opiates could near make you not feel your arm being chopped off, ibuprofen couldn’t prevent a light pinch from hurting.




There are prescription-grade NSAIDs that make Advil look like candy, but they're admittedly still not as heavy-hitting as bona fide painkillers. Great for inflammatory pain though.


They're also typically pretty rough on your GI systems. Though it's worth the trade-off, usually


Not just your GI, but they increase your risk of cardiovascular issues as well, among many others, whereas opiates do not cause any of those horrible side-effects. Dose matters, it does matter with NSAIDs, too, if I pop 10 acetaminophen, you can rest assured I will have liver cirrhosis.


Ha, also yes. Unfortunately I know this too well, but my GI systems are worse than the average person's :P




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