Right. There is clearly a powerful system in the human brain and body that controls our appetite and weight set point. Medications that adjust that system seem to produce durable changes in appetite and obesity, while typical changes to diet and exercise see weight revert to the mean after a year or so.
So the question is whether there are other substances in our diet that are also affecting this system. This isn’t crazy: various gut bacteria produce proteins that increase natural GLP-1 in the body. So any substance that disrupts these bacteria could easily have this sort of effect. https://www.nature.com/articles/s41564-021-00880-5
So the question is whether there are other substances in our diet that are also affecting this system. This isn’t crazy: various gut bacteria produce proteins that increase natural GLP-1 in the body. So any substance that disrupts these bacteria could easily have this sort of effect. https://www.nature.com/articles/s41564-021-00880-5