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That's probably a separate and harder problem from this: The A and B antigens refer to the presence of carbohydrates extending from the cell membrane, whereas Rh factor + refers to the presence of a protein.

Since there are different classes of bio-molecules, proteins may need different techniques to remove, alter, or cover them up.

If we do find such techniques, they may have much broader applications in immunology.




Rhesus factor is a lot more forgiving though: i.e. in a crisis you can transfuse rhesus positive blood to a rhesus negative person successfully since the sensitization doesn't emerge immediately.




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