Clotted cream is my greatest loss moving from Dartmouth, Devon to the US. A vanilla ice cream cone with clotted cream and a Cadbury flake is unparalleled. And a Mother’s Bread sandwich with clotted cream and strawberry jam being next in line.
There's clotted cream (and double cream, treacle, golden syrup, mixed spice, etc) in every major American metro I've ever been in. Look for a British import shop. Or, if you're in New England, SoCal, etc, you might just find domestically produced stuff (Gelson's in LA has it, for instance).