Reminds me of a widely circulated bit a couple years ago about this legendary climber, some doctors put him in an MRI and came to the conclusion that he basically doesn’t experience fear (mutation?). https://nautil.us/the-strange-brain-of-the-worlds-greatest-s...
The adeno-associated virus was an inert viral vector carrying a targeted antagonist that prevented the transmitter switching. The blocking agent was an anti-depressant.