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Relationship of sleep and depression is a very interesting topic that despite decades of observation and research is still poorly understood.

As other comments point out, the potential beneficial effect of sleep deprivation (SD) has been noted for a long time. It's also correct that effects tend to be transient and quite varied among study subjects.

A recent comprehensive meta-analysis [0] showed that overall, extant studies of sleep deprivation in depression are too inconsistent to allow drawing firm conclusions regarding its merit. To quote the authors, "...it is uncertain whether SD affects quality of sleep, health‐related quality of life, everyday functioning or length of hospital stay. Generally, the method is well‐tolerated, although the risk of switch to mania exists. Albeit the low grade of evidence, the treatment method of SD should be considered an important part of the future research in rapid relief of depression".

For clinicians, the careful scientific approach emphasizes need to accumulate clear evidence of efficacy and safety before prescribing SD to those suffering major depression.

[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839702




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