Serving at USDS, posting personally. The biggest thing with the gov is the requirements on usajobs are always explained specifically so you know exactly what is needed.
Beyond that, you'll want to show in your resume how you've delivered successfully and ideally in challenging circumstances, because working in the gov can be challenging. It will really vary depending on the job and agency.
To echo wslack, experiences with moving initiatives through grit and collegiality is key. The PIF program is a bit easier to apply for than USAjobs and really focuses on being more of an entrepreneur-in-residence, as much as that’s possible in government. I was able to work horizontally in a way that would have been challenging otherwise.