I definitely noticed. I used to get 70 spam emails a day and after the takedown that number went down to 4 to 7. So I'm very thankful for that.
Further proving that the war on spam is not in vain. I had always assumed it was futile because there's so many spammers, but over time I learned there's actually only a small number of spammers who are responsible for the majority of spam.
Just 94 billion per day. That's what I call optimism.