Realizing just how much of Hollywood is the result of pharmacology genuinely depressed me as a male for a bit, knowing those results are actually unattainable naturally
As GP said, you need the genetics, and to get the sort of body that Arnold or other top bodybuilders have you can't do it naturally.
However none of those things stops you from lifting weights for strength training, which is good for your body, your skeleton, your appearance, and your mental health. If your goal is to get strong, that is attainable naturally by anyone. You just need to do it.