In have ducted mini split units in my home, made by Mitsubishi I designed the system to work with merv 13-16 filters. I can run the fans and filter my air as well as use the units for heat and cooling. I installed fresh air intakes on the return units that can pull external air when they are opened.

It's really a very good proposition. Has all of the advantages of central heating and the efficiencies the heat pumps