I tried Alpine.js a very long time ago. Managed to build some small web apps with Haml[0], but never everything big. It's generally very easy to use but when it comes to scaling it doesn't scale very well. Building a todo app with it requies many lines of JS objects, combined with that every object is defined in a string makes the code look a bit ugly. Useful for prototyping and small web apps if you dont want to use complex stuff.

[0]: https://haml.info/