Yes, I was a burnt out software engineer in the defense industry and I found really meaningful work with a non profit that got me so excited. And I started my new job after a two week break and I was still burnt out. That sucked because I thought the break and the excitement for meaningful work would cure my burnout. I stayed with the job, kept working, albeit not at the pace I wanted due to the burnout and anxiety. I had been seeing a good therapist for years but just couldn't get out of the funk. What finally helped me was surprisingly acupuncture. I went for computer neck and it released a bunch of tension I was needlessly carrying, the physical result of trauma and anxiety. I am not saying acupuncture will necessarily work for you; rather, I think that seeing if there are underlying causes you can address rather than just changing your work situation seemed to yield more results. Good luck and I hope you find happiness!