As the other comment notes, I’m not sure if MAME can actually properly emulate any music hardware. There’s a skeleton Elektron Machinedrum/Monomachine in there for example but it can’t really do anything interesting (although this thread talks a bit about how some hackers used it to help reverse engineer and ultimately create their own firmware for the Machinedrum, see my other comment for more details: https://github.com/jmamma/MIDICtrl20_MegaCommand/issues/88)
Another project which may be of interest is this emulation of the Motorola DSP536xx DSP, which was used in a lot of classic late 90s hardware synths: https://dsp56300.wordpress.com. It can actually run Access Virus ROMs pretty much perfectly and apparently on an M1 the performance is pretty good, it’s usable but crackly on my i9 Mac. They’re hoping to be able to emulate many more synths which used the same DSP but for now the Virus is the focus.
As the other comment notes, I’m not sure if MAME can actually properly emulate any music hardware. There’s a skeleton Elektron Machinedrum/Monomachine in there for example but it can’t really do anything interesting (although this thread talks a bit about how some hackers used it to help reverse engineer and ultimately create their own firmware for the Machinedrum, see my other comment for more details: https://github.com/jmamma/MIDICtrl20_MegaCommand/issues/88)
Another project which may be of interest is this emulation of the Motorola DSP536xx DSP, which was used in a lot of classic late 90s hardware synths: https://dsp56300.wordpress.com. It can actually run Access Virus ROMs pretty much perfectly and apparently on an M1 the performance is pretty good, it’s usable but crackly on my i9 Mac. They’re hoping to be able to emulate many more synths which used the same DSP but for now the Virus is the focus.