What DRM anticheat measures do is to monitor your whole system for modifications and kill the app if they detect changes. For example, they will make sure that your nVidia (or AMD) driver is one of the whitelisted hashes and hasn't been modified with a wallhack.

This is why Linux users using Wine keep being banned from these platforms - they detect "unusual" runtime environment and ban the players because it doesn't fit into their narrow hash of an "acceptable" system.

It is an outright definition of sealing off your OS from modification.