So this is a weird thing to think, because Amazon Linux 2 was never a drop-in RHEL replacement. It was a bastard child between RHEL 7 and Fedora stuff, combined with a custom kernel. You didn't have RHEL kABI and you didn't even have complete RHEL userspace compatibility either.

If anything, Amazon Linux 2022 clarifies things by indicating they directly track Fedora Linux, branch and stabilize that, and offer their own lifecycle guarantees for that branch.