This number of mutations isn't enough to completely change the mechanics of the virus. It's still the same thing in different clothing which might be enough to pass through the vaccine firewall, but the lethality won't be much different. I don't have to be a biologist to apply basic logic.
> This number of mutations isn't enough to completely change the mechanics of the virus.
One mutation can be enough, if its the right mutation.
> I don't have to be a biologist to apply basic logic.
Basic logic only helps if you start with accurate premises, which having an understanding of the relevant biology helps a lot with. Otherwise, you end up with GIGO.
> This number of mutations isn't enough to completely change the mechanics of the virus.
Maybe. Maybe not. The majority of the mutations in the B.1.1.529 genome are expressed as changes in the spike proteins but others are not and remain to be better understood. It is too early to tell what effects those remaining mutations will have on the lethality of this variant. If those mutations result in more efficient intracellular replication or other changes in intracellular viral life-cycle efficiency, then the morbidity and mortality may be greater, independent of immunologic escape.
well at least you're not making sweeping generalizations with no references/citations/sources on a field of research you admittedly aren't a part of...
