Israel would have had zero issues with Iran if Iran wasn't on a quest to destroy Israel. In fact the two had normal relations until the Iranian Islamic revolution.
Ultimately the reasons why israel and iran are at odds don't matter much. Both are competiting to be regional powers in the middle east, and its the lines which alliances are being drawn around.
The point is swap out the people in those geographies, rerun the timeline, and you’ll find them in conflict. The reasons they each come up with in this iteration is dressing.
> The reasons they each come up with in this iteration is dressing
What reasons do you think Israel "has come up with"? To me it's quite clear there's one side that's bent on destroying the other, there is no symmetry.