> some of the molecules you proposed have pretty large functional groups adjacent to rings
And many more do not.
> if you took those molecules and gave massive doses to rats, some may comeback as carcinogenic.
Luckily we don't have to guess. For example, look at the hundreds of terpenoids that saturate traditional diets, many of which and are widely believed to prevent cancer. If you have any actual evidence, put it up.
> The multi ring structure to me suggests...
All this is interesting, but it has exactly nothing to do with in vivo carcinogenicity. You don't have to look far to see this is true. Healthy diets are chock full of polyphenols that exhibit significant DNA binding affinity, but lack evidence of carcinogenicity. And it's not for lack of looking.
You appear to have some specialized knowledge, but when you try to extrapolate it to a wider field where you're out of your depth, these hand-waving guesses can easily turn into fearmongering.
I want to apologize, I definitely don’t intend to fear monger and most definitely not want to imply that I have expertise. Roughly my level of understanding is mostly that of a low level undergrad and you should treat my naiveness as such.
I recognize that what I’m engaging in is entirely wild speculation based on limited experience and data, likely very error prone and that really I’m just having fun without considering how it may impact other readers.
I understand that for many this an important issue of health and research. I did not intend to detract from these more legitimate forms of discussion.
And many more do not.
> if you took those molecules and gave massive doses to rats, some may comeback as carcinogenic.
Luckily we don't have to guess. For example, look at the hundreds of terpenoids that saturate traditional diets, many of which and are widely believed to prevent cancer. If you have any actual evidence, put it up.
> The multi ring structure to me suggests...
All this is interesting, but it has exactly nothing to do with in vivo carcinogenicity. You don't have to look far to see this is true. Healthy diets are chock full of polyphenols that exhibit significant DNA binding affinity, but lack evidence of carcinogenicity. And it's not for lack of looking.
You appear to have some specialized knowledge, but when you try to extrapolate it to a wider field where you're out of your depth, these hand-waving guesses can easily turn into fearmongering.