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Launch HN: FirstIgnite (YC S21) – Matching scientists with relevant businesses
72 points by codypilot on Aug 13, 2021 | hide | past | favorite | 33 comments
Hi, HN! I’m Cody Pawlowski and my co-founder is Chase Bonhag and we’re FirstIgnite (https://firstignite.com/). We help researchers at universities connect with companies interested in funding or licensing their research.

Currently, a vast majority of all research goes uncommercialized. This includes everything from new cancer therapies to energy storage improvements and other solutions to universal problems. By connecting research to relevant companies, we increase the probability that research will be commercialized.

We met while I was running a natural language processing startup at the University of Illinois at Urbana-Champaign. Chase was working at Illinois Ventures, the venture capital arm of the university. U of I conducted over $900M a year worth of research, much of which was going uncommercialized. Because university research portfolios are massive, diverse, and highly complex, it's nearly impossible to figure out which companies to partner with for which research. We realized that we could apply NLP to the problem because it was written in scientific text via patents and publications!

We started by taking unpaid pilots from universities in fall of 2019. Seven schools gave us two pieces of research to match to industry. For 6 of the schools, we completely failed and were unable to connect any of their research to companies. But for one school, we managed to connect both of their technologies to 5 companies each. We learned that patent databases had company interest and activity in text format that matched well to research publications. We also learned that matching to patents was not quite enough, but if we also looked at the competitors of those holding patents we were able to identify a large enough top-of-funnel to find success on almost any topic. We built our initial product and process around that approach.

Researchers upload scientific documents describing their research and receive tailored lists of companies interested in that research. Using natural language processing and graph theory, our software analyzes the texts and matches their research to industry activity consisting of nearly 3 billion relationships stored across public and proprietary data. We’ve had success mainly leveraging USPTO full-text and competitive intelligence data, with plans to bring in European patents, SBIR, clinical trials, job postings, corporate filings, press releases, social media, and any other text that hints at what a corporation is interested in.

What’s unusual is that we’re the only solution that allows you to upload a piece of research and receive a tailored list of companies and leads to contact. We call this active marketing—helping researchers get in touch with those who are most likely to move their research forward—as opposed to a passive marketing approach, where researchers upload their technologies in hopes of companies reaching out to them (of course, they usually don’t). Our approach results in an average of 5 meetings with companies per scientific document vs our competitors' passive approach which is lucky to result in 1 meeting. We currently make money by selling software and service subscriptions to universities.

Some examples: Professor Chou at the Children's Hospital of Philadelphia uses our tool to identify companies working on cancer therapies and connect with them about potential research partnerships. Carnegie Mellon University uses our software to market "moonshot" research topics to companies to identify future funding partners. UC Davis uses our tool to identify companies interested in licensing their intellectual property.

We’re really excited to share FirstIgnite with this community. We’re open to all thoughts and ideas, we’d love to learn about experiences you’ve had working on research projects, things you know about university research or corporate R&D, or anything else that can help us. Thank you!




It might be worth considering a change of framing: Instead of helping researchers find a company to commercialize their research (solution looking for a problem), give companies a way to find researchers who can help them solve their problems (problem looking for a solution).


Great insight! More than a change of framing it's also something we're beginning to explore and productize. At first, it was easy for us to view the tens of thousands of unlicensed university technologies as a problem, but now it seems to be more of a solution to the problem of corporate R&D not knowing who exactly they should be getting in touch with. Push vs pull if you will.


Yes! I'm so glad you commented this. We actually ended up focusing on universities due to the pandemic last year and having to stay hyper focused. But, we're in process of preparing to launch our company need --> scientific expertise tool. This is a much larger market and we can't wait to kick things off.


AcademicLabs.com is known to be the leader in this space with a sophisticated platform, used by ao most big pharma. Some other players as well. Best to carve out your own unique niche like you're doing now and then you can see how to grow from there.


I missed this previously. AcademicLabs has an impressive platform! We're carving our niche and learning every day. The biggest thing for us is helping scientific breakthroughs get to market, faster. Cheers to what is ahead!


I agree. Phd students are often not particularly wealthy and may have to pay for this service out of their own money. Companies looking for specific expertise however are likely to have funds for it, and be more than willing to pay for a good service.


Great point. The good news is we're offering our tool for free to PhD students right now as we work to get universities to cover sitewide licenses for faculty and students.


My university at least had a commercialization office. I imagine that they are the ones paying for it in this model.


Yes - the majority of our current customers include the tech transfer, corporate relations and VP of Research offices.


This is a great problem space!

As mentioned by an other commenter, from the industry point of view it is quitte hard to find the good researchers.

I worked on campus (both in Europe and US) for a Major insurance company trying to help with corporate R&D and there have been a lot of hurdle (see it as a list of pain points I faced when trying to collaborate with universities) :

- Some researcher are a little too much focus on their area on expertise and will refuse to work on their research outside of the field they have in mind, because either "nobody need it for that, it's mean for [insert previous research project of researcher]". Ex: We need some really precise Geolocation to estimate the level of a river bed for flood estimation near industrial site, found the good lab / researcher (previous paper in the space solving similar problem albeit not for river), go to them ready to propose a grant to work on the topics, not interested to work on river.

- Almost no researcher will want to work on a field that is view as 'solved', as they will not be able to publish. Ex: We are desesperate for better OCR tech, as we have an archive of hundreds of millions of document we need to make sense of. No machine vision / CS lab we approach want to do some research in this field as it is solved. Yet in reality the technology is generally not accurate enough on print character. Same story with Handwritten Character Recognition.

- Some researcher will try to promote their implementation of their research, but generaly the quality of the implementation is far from what we expect to put in production, and generally have little UX / modern stack understanding, if you are lucky it's implemented in JAVA, but a lot of things are a python notebook, some R or MatLab. They will however not want to collaborate on a industry ready implementation and try to push their implementation they are in love with.

If you were to fix this pain points, and provide a tool allowing for discovery this will really be great (and I will be happy to use it).

However the really interesting collaboration emerge when you approach a lab for use of their research in a tangent field they didn't anticipate. I wonder if you could automate/accelerate/facilitate this with machine learning or something else.


Wow! This is a great response. I'd love to find time for a chat, my email is chase@firstignite.com


Another question. Have you heard of companies like Innocentive and HeroX? They seem to be at the other end of this, where companies put out a call for solutions and have a cash prize for them, as well as the opportunity for future partnerships.

https://www.innocentive.com/#challenges

https://www.herox.com/crowdsourcing-projects?from=home


These are great. We knew about Halo.science but had not heard of these other two. I think it's a great model and these appear to be having good success. We really want to be involved in the transaction of scientific R&D projects, playing a larger role facilitating them, so will have to study these groups more.


A few people have mentioned marketing to companies who want the service, and I'll say, that's more inline with what I'm looking for.

We come from a research organization (CSIRO) and are in the sleeptech space. We thought we were pretty well connected into research, but we're still spending quite a bit of time tracking down the right people and getting intros. Getting a project going is another step beyond that.

This is in the situation where we know what research we want conducted. Do you see this fitting into your business model in the future? How would you see IP being managed in that environment?


Have you considered marketing this to universities directly? I'm sure many universities these days have "knowledge transfer/commercialization" offices that would be interested in this.


This is who we market it to! We're actually currently working with ~30 universities and national labs in the US. We work with the commercialization and corporate relations office (and a few deans of colleges as well).


Do you do anything to help the researchers make better marketing materials/give better pitches?

Anecdotally, I was part of an accelerator where some participants were given the option of commercializing something the university had and researchers came and gave us pitches on things they thought should be commercialized.

The pitches were terrible. About half the time nobody in the cohort had a grasp of what the IP was after the pitch had ended. Sometimes we were not sure of the industry.


This is a great point. We realized early on that researchers present their research to industry as if they are giving a lecture to a group of peers; 45m of presenting without any response from the crowd. We try to work with our users to help them understand how to present their research in 5m or less in terms that industry will find interesting, but it's a constant battle. We're working on features to help with this!


I'm curious — what is negotiating with tech transfer offices like? I'm sure they're receptive to your idea, but how do you negotiate fees and %s? We've seen that it's often hard for TTO and others to agree on a "true value" of their IP, and they sometimes think their IP is worth millions when sometimes it's worth thousands.


Let's be careful about proclaiming a new space and offering. This product space has existed for a few years now. There are companies providing matching algorithms between an uploaded tech abstract/patent/publication and interested companies (as well as for companies seeking academics). My own company already provides this exact service in Scout (wellspring.com) and we have competitors, some mentioned below. We have 100's of clients. So, do some of our competitors. This just isn't new.


It's such an amazing market to support! Playing any role in helping scientific breakthroughs get to market is a noble cause. We share many of the same customers and they don't describe your offering as competitive to ours, in fact, in most cases they subscribe to both! They refer to wellspring as a passive marketing approach while dubbing ours an active marketing approach. The difference being is with FirstIgnite you will get the email addresses of those to reach out to, which isn't something they are getting from Wellspring.


I did a empirical study on CI/CD and finding companies to participate took a lot of time. If your platform could connect me to people and companies who want to get better at processes like CI/CD I can help the company out and they can help me out by being a company versus an open source project. Open source is easier to get access but does development differently than companies so findings in open source are not always generalizable to companies.


Could you just index Google Scholar or ResearchGate profile? Also, why isn't ResearchGate doing something like this? They already have a job board.


Great project! For anyone interested in the UK, there is a similar-ish (government funded) scheme called the "knowledge transfer partnership" [1], which connects academics and their research to businesses where it can be usefully applied.

[1] https://www.ktp-uk.org


Very cool. We'd love to connect with more UK universities and researchers as we currently only have US customers.


Researchers usually don't reach to companies since the university owns the IP and they have a licensing office that does this function. Is it a tool for them?


For sure! Researchers can use the platform to find existing solutions or opportunities in the market. If there's a strong match then they could pursue a sponsored research agreement or simply get in touch for feedback and further opportunities.


It's not clear from your website how a PhD looking to connect with suitable industry opportunities would use the service?


This is true, our typical user works within a tech transfer office or OVPR so much of our content is tailored to their needs. However, our approach of uploading research material and receiving lists of relevant companies is also effective at helping PhDs discover industry opportunities!


Is this US specific? (asking from the UK)


Not specific for US. Although we currently support mostly US universities and national labs, we can work with any piece of research or technology and match to global companies and contacts.


This sounds a lot like Niels Reimers as a service. Am I understanding this correctly?


Wow! Yes, we're applying technology to help make it so everyone can be as effective as Niels!




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