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By that standard, you also can’t rule out disease-induced ADE, dengue style.

But the vaccine developers do know what they’re doing. IIRC, with SARS, a lot of research was done that suggested that antibodies against N might cause ADE but antibodies against S would not. If that carries over to COVID, then maybe one is better off with a vaccine than natural disease: the latter induces antibodies against N but the former does not.




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