More up to date kernel (and associated bits) means usually the best support for hardware (e.g. Fedora is usually faultless on Lenovo laptops, unless you have GPU problems).
More up to date and more vanilla Gnome means that you've got the best state of Wayland implementation, and therefore the best version of multi-monitor, HighDPi etc. (I don't know what Ubuntu is like here though at the moment).
More up to date and more vanilla Gnome means that you've got the best state of Wayland implementation, and therefore the best version of multi-monitor, HighDPi etc. (I don't know what Ubuntu is like here though at the moment).