Originally only two person chats were e2e encrypted, then the added e2e to group chats, but last time I checked (admittedly a year or more back) if one participant in a group chat had an old version of the app, the entire group chat was unencrypted, without an obvious user interface indication of that.
I use (and trust) Signal. I believe Wickr is trusted by people who have resources behind them to know whether it's trustworthy (though it's closed source, so :shrug:).
If you need "used by the masses", then you're gonna be stuck with, I dunno - Facebook public posts? Gmail? Slack? Smoke signals? Nothing that's fit for purpose" if you value privacy...
Do you have better recommendations which use E2E and are also already used by the masses?