I suspect a ton of the psychological illnesses/problems we see today are the result of radical divergence from the behaviors we had in our ancestral evolutionary environments. It would be remarkable if the brain didn't make a bunch of assumptions on the structure of our environment when tuning stimulus sensitivity, neurotransmitter production, etc.
Some examples that seem obviously concerning to me are changes in child-rearing patterns (later and fewer), changes in diet (less fat and protein, more stuff that didn't exist in the evolutionary environment at all), changes in stress exposure (mental, physical, and immune [especially parasitic]).
Some examples that seem obviously concerning to me are changes in child-rearing patterns (later and fewer), changes in diet (less fat and protein, more stuff that didn't exist in the evolutionary environment at all), changes in stress exposure (mental, physical, and immune [especially parasitic]).