I've shot a ton of Kodak Ortho film in 4x5 at EI 3, 6, and 12. It's actually super easy to develop. I recommend stand development in 1:100 HC-110 with occasional agitation. The developer basically exhausts after 10 or 12 minutes depending on the temperature, which happens to be pretty much exactly the right development time, so it's pretty much impossible to over-develop.