You'd be surprised as to what constitutes interstate commerce. I've seen local criminals brought up on federal Hobbs Act charges for their participation in robbing convenience stores. The prosecutor made sure to note that the store was "known to engage in interstate commerce." Almost any business you can think of engages in interstate commerce. Think about it, where does the stock for the store come from? Where were the registers used to process transactions manufactured? Does the business purchase digital advertising? All of those are interstate commerce.
I'm not surprised, because I'm already aware the umbrella is rather larger than most people would expect. Nevertheless, it simply won't cover everything that we'd need covered from a public health perspective. So what happens here?
That only means the federal government can pass a law about it. It doesn't mean they can pass a law that abrogates other constitutionally-protected rights.