Your comment led me to look up the origin of the name "Lyme disease":
Lyme disease gets its name from a small coastal town in Connecticut called Lyme. In 1975, a woman brought an unusual cluster of pediatric arthritis cases to the attention of Yale researchers. In 1977, the Yale researchers identified and named the clusters “Lyme arthritis." In 1979, the name was changed to "Lyme disease," when additional symptoms such as neurological problems and severe fatigue were linked to the disease. In 1982 the cause of the disease was discovered by Dr. Willy Burgdorfer. Dr. Burgdorfer published a paper on the infectious agent of Lyme disease and earned the right to have his name placed on the Lyme disease spirochete now known as Borrelia burgdorferi.
As an ex smoker I disapprove of the idealizing depiction of cigarettes. Nevertheless I find the project very interesting and wonder if you are willing to share the code?
People interested in this should make sure to see the later post too:
https://stuffmatic.com/blog/making-a-pentagonal-tiling-puzzl...
The rest of your site is fascinating too. Can't wait to see what else you come up with!