Scale reduces diversity which increases vulnerability. Darwin would interrogate this potentiality in the following way(essentially articulating the characteristics and benefits conferred by his evolutionary model) : reproduction can essentially be viewed as scale in this kind of context: a turtle's reproduction produces lots of turtles, rather than a random assortment of lifeforms such as snails and rabbits, etc. In this sense, biological reproduction results in the 'scale' of some particular thing, i.e., 'more of the same', rather than 'different every time', i.e., differentiation, or diversity. The vulnerability produced by scale in this context is that some peril resulting from a change could render all instances of the scaled thing extict. Nature produces the differentiation required to increase survival chances in such circumstances by mutation taking place in the course of reproduction. What the OP's concern seems to introduce, at least from my perspective, is an argument for exploring the options and practicalities for considering the possibility of somehow contriving something akin to a 'mutation imperative' into the design policy leading up to the development of scaling processes, in order to introduce at least some potential for the level of differentiation to constitute a potential for adaptation and thereby confer a potential for survival in the face of what might otherwise be an extinction level event. It's kind of like advocating applying some kind of 'resilience theory' to 'scalable innovations', no? I don't know if anyone has already proposed or even implemented this approach elsewhere.