Basically, if you're planning on pointing a laser into the sky, you need at a minimum issue a NOTAM to inform aviators of the hazard. Things like outdoor concerts and some weather observation systems do this.
But... Sending a laser into the sky and intersecting an aircraft that was operating per regulation? That's on the laser-er, and "creating a hazard to aviation" is not a charge that you'll be happy dealing with in many countries.