If your state of consciousness is altered by 2% that's just called a normal day.

There is a very qualitative difference between tripping and not-tripping. (With a blurry line but you can easily stay on one side of a blurry line.)

It's uncertain if microdosing a particular ligand has any scientifically-proven evidence of efficacy without studying it. In many instances, it maybe a shared delusion placebo effect and/or socially-reinforced fad.