Yup, I use it as my main development PC - I have a runtime for my project that runs on Fedora, but the main target is a Gentoo distribution.
As others have noted, it's a bit more cutting edge than Ubuntu, which is fine, but some times cutting edges leaves you bleeding. I prefer to stay one step behind, ie now that Fedora 14 is out, it must be about time for me to move to Fedora 13 :) I find that the first 3 months or so of a distribution's life cycle tend to be a bit unstable, but you could probably safely upgrade after that time, no need to stay an entire cycle behind like I do, it's just that I tend to be rather cautious!
As others have noted, it's a bit more cutting edge than Ubuntu, which is fine, but some times cutting edges leaves you bleeding. I prefer to stay one step behind, ie now that Fedora 14 is out, it must be about time for me to move to Fedora 13 :) I find that the first 3 months or so of a distribution's life cycle tend to be a bit unstable, but you could probably safely upgrade after that time, no need to stay an entire cycle behind like I do, it's just that I tend to be rather cautious!