The Mac user consensus seems to be that the panel is great, but everything around it is flakey (at least compared to previous Apple displays) - plugging and unplugging doesn't work 100% of the time, stuff like OS integration of brightness and volume keys isn't seamless etc. Looking at user ratings it seems like reliability isn't great either but that could be skewed.
Anecdotally... I bought an LG Ultrafine 5K when they came out - I believe I've got one of the initially faulty ones that can't go too close to a WiFi access point due to lack of shielding.
It was flaky as hell when it first came out but over the course of about a month of receiving it, the problems largely seemed to stop occurring.
I typically unplug and plug it in once per day when I take my Macbook Pro away to sit somewhere else in the evening. But when I'm working during the day I use it as my primary display. For my own experience the integration of brightness and volume is seamless. The speakers are good (although I use some old Genelec monitors instead for this), and the quality of the display is absolutely fantastic as you said.
About one in fifty times plugging it in to the laptop doesn't immediately work, and then I plug it into a different USB-C port on the laptop, and then it does.
Just one data point: I have two of those screens connected to an iMac Pro. This is a setup officially supported by Apple, but sometimes when waking up the Mac one of the displays doesn't turn on and the only option to get it back to work properly is disconnecting either the power or the USB cable.
This is reproducible by connecting both screens to a 15" MBP Pro 2016.
If the screens would at least have an ordinary power switch so I would have to crawl over my desk once every two weeks my life would be a lot better,...
