nginx in front of gunicorn is fast, simple, efficient with resources, and reasonably scalable. Today, there's nothing else I would recommend.
Of course, use [d]vcs, setup.py, virtualenv, pip, and south (and a reasonable test suite!). Using these along with gunicorn as mentioned above has streamlined my deployment to a "one-click" process that leverages all of these packages to create an isolated, repeatable, rock-solid [re-]deployment with nothing more than a generic Makefile.
I've been doing Django development and deployment for over four years now and it is the closest thing to a "silver bullet" I've found.
Of course, use [d]vcs, setup.py, virtualenv, pip, and south (and a reasonable test suite!). Using these along with gunicorn as mentioned above has streamlined my deployment to a "one-click" process that leverages all of these packages to create an isolated, repeatable, rock-solid [re-]deployment with nothing more than a generic Makefile.
I've been doing Django development and deployment for over four years now and it is the closest thing to a "silver bullet" I've found.